PATIENTS    |   BECOME A PROVIDER    |   PROVIDER PORTAL    |   PROVIDER SEARCH    |   REIMBURSEMENT

SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02

SoftWave Celebrates Pro Success of Golfer Jake Peacock and Baseball Player Reid Worley, Highlighting Injury Prevention Breakthroughs

,

TISSUE REGENERATION TECHNOLOGIES, LLC Establishment Registration & Device Listing

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy

The beneficial effects of in vitro shock wave treatment on cardiomyogenesis are energy dependent

Regenerative Skin Treatment for Burns, Scars, and Wounds

Regenerative Skin Treatment for Burns, Scars, and Wounds

,

Lohse – Busch ISMST Presentation

UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors

Focal Shockwave Therapy Mechanisms and Efficacy Explained

Focal Shockwave Therapy Mechanisms and Efficacy Explained

Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

​Prospective randomized phase II trial of accelerated reepithelialization

Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.

Shockwave Therapy as First-Line Treatment for Peyronie’s Disease: A Prospective Study

Extracorporeal shockwave therapy induces alveolar bone regeneration

Shock wave treatment after hindlimb ischemia results in increased perfusion and M2 macrophage presence

Analysis of extracorporeal shock wave therapy for Peyronie’s disease

Extracorporeal shockwave therapy (ESWT) First choice treatment of fracture non-unions?

Extracorporeal Shock Wave Treatment: An Emerging Treatment Modality For Retracting Scars of The Hands

MTS Spark WaveTM Technology and its mechanism of action in wound management

Principles of Shock Wave Therapy

Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment

Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-β1

Extracorporeal shock wave therapy for the treatment of coccydynia: a series of 23 cases

,

Efficacy of extracorporeal shock wave therapy (ESWT) for males chronic pelvic pain syndrome

Shockwave Therapy Helping Patients With Peripheral Artery Disease

Shock waves promote spinal cord repair via TLR32

​STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

,

​Antibacterial effects of extracorporeal shock waves

Effective Medical Devices for Treating Uterine Fibroids

Effective Medical Devices for Treating Uterine Fibroids

The effect of shock waves on in vitro cartilage development in silk scaffolds

Extracorporeal Magnetic Transduction Therapy Explained

Extracorporeal Magnetic Transduction Therapy Explained

Extracorporeal shock wave therapy (ESWT) in urology:a systematic review of outcome in Peyronie’s disease, erectile dysfunction and chronic pelvic pain

Baker’s Cysts

Best Medical Devices for Treating Baker’s Cysts

SoftWave’s New Leadership Team Accelerating Commercial Growth and Market Expansion

Test12343

Erectile Dysfunction before and after results under ultrasound

​Extracorporeal shock wave therapy in periodontics: A new paradigm

Exploring Regenerative Treatment for Knees After Failed Conservative Care

Regenerative Treatment for Knees That Fail Conservative Care

Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

Extracorporeal shockwave therapy (ESWT) ‒ First choice treatment of fracture non-unions

Shockwave Therapy Of The Heart​

Softwave® Tissue Regeneration Technologies Announces Landmark Trial for Acute Traumatic Spinal Cord Injuries

Shock wave therapy for acute and chronic soft tissue wounds: A feasibilty study

A prospective, randomized, controlled, single centre trial to assess the efficacy and safety of radial extracorporeal shockwave therapy in patients with chronic non-specific low back pain

,
Storz Modulith Shockwave Systems- Mechanisms, Clinical Context, & Alternatives

Storz Modulith Shockwave Machines: Efficacy & Alternatives Explored

,

Can You Use a Shockwave Therapy Machine at Home?

Effectiveness of extracorporeal shock wave for low back pain (A protocol of systematic review)

,

Shock wave therapy enhances neuronal sprouting and improves neuronal survival

Erectile Dysfunction and the Shocking Truth: Is Shockwave Therapy Effective

2025 AUA Guidelines on Male Chronic Pelvic Pain: Shockwave Therapy Evidence and Clinical Implications

Effective Medical Devices for Temporomandibular Joint Dysfunction

Effective Medical Devices for Temporomandibular Joint Dysfunction

Penile low intensity shock wave therapy for PDE5i non-responders suffering from vasculogenic Erectile Dysfunction since 2 to 10 years: A prospective, randomized, placebo-controlled study

Prospective Randomized Phase II Trial of Accelerated Reepithelialization of Superficial Second-Degree Burn Wounds Using Extracorporeal Shock Wave Therapy

,

Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

The Basic Science Behind Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

Shockwave treatment enhances cell proliferation and improves wound healing

Plantar Fasciitis Medical Devices That Relieve Pain

Plantar Fasciitis Medical Devices That Relieve Pain

Unfocused extracorporeal shock waves induce anabolic effects in rat bone

Extracorporeal shockwave treatment for chronic diabetic foot ulcers

,

​Exosomes and Cardiovascular Protection

IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

What Is Pneumatic Shockwave Therapy?

What Is Pneumatic Shockwave Therapy?

Extracorporeal shockwave therapy versus exercise program in patients with low back pain: short-term results of a randomised controlled trial.

,

DIGEST Guidelines for Extracorporeal Shock Wave Therapy

Do Gymna Shockmaster Machines Work for Patients?

Do Gymna Shockmaster Machines Work for Patients?

Zimmer enPulsPro Shockwave Machines-

Zimmer enPulsPro Shockwave Machines: Efficacy & Alternatives

What Is EPAT Therapy & How Does It Work?

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Why SoftWave Is the Proven Standard in Regenerative Medicine Devices

Shock wave therapy for systemic sclerosis

,

Extracorporeal Shockwave Therapy vs Ultrasound Therapy for Plantar Fasciitis

Best Physical Therapy Devices Clinics Must Have

Best Physical Therapy Devices Clinics Must Have

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

,

AUVA letter‒ Successful treatment of delayed and non-union fractures

Athletic therapy (Mts-Science)

Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite

Shock wave-pretreated bone marrow cells further improve left ventricular function after myocardial infarction in rabbits

Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

Efficacy of Extracorporeal Shockwave Therapy on Pain and Function in Myofascial Pain Syndrome of the Trapezius: A Systematic Review and Meta-Analysis

Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves

What Is Li-ESWT & How Does It Work?

Best Medical Devices for Treating ACL Injuries 

Best Medical Devices for Treating ACL Injuries 

Best Medical Devices for Treating Carpal Tunnel Syndrome

Best Medical Devices for Treating Carpal Tunnel Syndrome

Piezowave Therapy Efficacy & Alternatives Explained

Piezowave Therapy Efficacy & Alternatives Explained

Extracorporeal shock wave therapy (ESWT) for the treatment of cellulite e A current metaanalysis​ -(Plastic, Hand and Burn Surgery, University of Schlewig Holstein, Lubeck, Germany​)

Motor and Sensory Schwann Cell Phenotype

, ,

Pilot Trial, First Report Worldwide for Li-SWT (unfocused SoftWaves) For the Treatment of Testicles to Improve Testicular Size and Function.

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

Electromagnetic Shockwave Therapy Mechanisms & Efficacy

Lateral epicondylitis: This is still a main indication for extracorporeal shockwave therapy

Shock wave treatment of muscle stem cells – a new implementation for regeneration

Fully healed, Ordonez flourished for Tigers using ESWT

Improved rate of peripheral nerve regeneration induced by extracorporeal shock wave treatment in the rat

Angiogenic response to extracorporeal shock wave treatment in murine skin isografts

Assessment of IL-1Beta and VEGF Concentration in Rat Model During Orthodontic Tooth Movement and Extracorporeal Shock Wave Therapy

Low-energy shock waves treatment induces angiogenesis in ischemic muscle by stimulation of Toll-like receptor 3 signalling

Can cellulite be treated with low-energy extracorporeal shock wave therapy?

Pulsewave Therapy- Mechanism of Action and Clinical Indications

Pulsewave Therapy Explained: Mechanism of Action and Clinical Indications

Cellulite and focused extracorporeal shockwave therapy for non-invasive body contouring: a randomized trial.

Radial Extracorporeal Shock Wave Therapy to Support Breathing In Case of Coronavirus Disease 2019 (COVID-19): A Case Report

Benefit of combined extracorporeal shock wave and bone marrow-derived endothelial progenitor cells in protection against critical limb ischemia in rats

​Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

New Treatment Option for Clinical and Subclinical Mastitis in Dairy Cows Using Acoustic Pulse Technology (APT)

Shockwave Therapy Contraindications- When Not to Use It

Shockwave Therapy Contraindications: When Not to Use It

Shock waves induce angiogenesis via exosome release

,

Extracorporeal shock wave therapy relieved pain in patients with coccydynia: a report of two cases

,

Extracorporeal shock wave therapy surpresses the early proinflammatory immune response to a severe cutaneous burn injury

Neuropathy

Shockwave Therapy for Neuropathy

The influence of comorbidities and etiologies on the success of extracorporeal shock wave therapy for chronic soft tissue wounds: midterm results.

Pickleball Star Riley Newman Speeds Recovery With SoftWave Therapy

Mesenchymal stem cells: Myths and reality

In Situ Activation of Penile Progenitor Cells With Low-Intensity Extracorporeal Shockwave Therapy

Regenerative Therapies for Hip Pain and Tendinopathy

Regenerative Therapies for Hip Pain and Tendinopathy

Test43212

Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s disease

Prospective randomized trial of accelerated re- epithelization of skin graft donor sites using extracorporeal shock wave therapy

Extracorporeal Shock Wave Device for Treatment of Chronic Burns

Ultrasound and shock-wave stimulation to promote axonal regeneration following nerve surgery

Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

Extracorporeal shock wave therapy for calcifying tendinitis of the shoulder

Set up Instructions

,

Evidence supporting extracorporeal shockwave therapy for acute and chronic soft tissue wounds

Renova Shockwave Therapy- What Is It & Does It Work for Patients?

Renova Shockwave Therapy: What Is It & Does It Work for Patients?

Review of the Current Status of Low Intensity Extracorporeal Shockwave Therapy (Li-ESWT) in Erectile Dysfunction (ED)

Extracorporeal Shock Wave Device for Treatment of Chronic Wounds

The Physics of Shock Wave Lithotripsy

Effects of Shock Waves on Expression of IL-6, IL-8, MCP-1, and TNF- alpha Expression by Human Periodontal Ligament Fibroblasts: An In Vitro Study

Molecular changes in diabetics foot ulcers

The Assessment of New Bone Formation Induced by Unfocused Extracorporeal Shock Wave Therapy Applied on Pre-Surgical Phase of Distraction Osteogenesis

Best Medical Devices for Treating Tennis & Golfer’s Elbow

Best Medical Devices for Treating Tennis & Golfer’s Elbow

Alternative Treatment using Shockwave for Erectile Dysfunction

SoftWave on Elbow

Why Chiropractors Choose Shockwave Therapy

Complementary effect of L-citrulline supplementation on SparkWave™ therapy-induced angiogenesis and regeneration

Evaluation of a low-intensity shockwave therapy for chronic prostatitis type IIIb/chronic pelvic pain syndrome: a double-blind randomized sham-controlled clinical trial

Extracorporeal Shockwave Treatment Impedes Tooth Movement in Rats

,

Extracorporeal shockwave therapy for atrophic and oligotrophic nonunion of tibia and femur in high energy trauma patients. Case series.

Cleveland Clinic – Low Intensity Shockwaves In Urology

Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

Symptomatic treatment of unresponsive wakefulness syndrome with transcranial focused extracorporeal shock waves

,

Extracorporeal shockwave therapy shows site-specific effects in osteoarthritis of the knee in rats

Morton's Neuroma

Effective Medical Devices for Treating Morton’s Neuroma

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptomes in a first-in-man trial

ESWT for retracting scars of the hand

ESWT minimizes ischemic tissue necrosis…

Using acoustic therapy to prevent opioid addiction.

Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database

Current concepts of shockwave therapy in stress fractures

Veterinary wound care case study

Project: SoftWaves to prevent opioid addiction and to help addicts in their recovery.

Extracorporeal shock wave treatment of capsular fibrosis after mammary augmentation

Heart Regeneration becomes Reality!

​Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells

Shock wave treatment for in vitro engineering applications

Evaluation of the LithoGold LG-380 lithotripter: in vitro acoustic characterization and assessment of renal injury in the pig model

​The biologic effects of SoftWaves and rationale for spine and brain therapy

Dr. Lohse Bush, first brain treatments

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement—a randomized clinical trial​

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

,

Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers

Chattanooga Intelect Shockwave Machine- Evidence, Mechanisms, and Clinical Context

Chattanooga Intelect Shockwave Machine: Efficacy & Alternatives

Minimally invasive treatment of Peyronie’s disease: evidence-based progress

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

Comparative analysis of angiogenic gene expression in normal and impaired wound healing in diabetic mice: Effects of extracorporeal shock wave therapy

A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

Limited shock wave therapy vs sham treatment in men with Peyronie’s disease: results of a prospective randomized controlled double-blind trial

SoftWave OrthoGold

Best Medical Devices for Treating Wrist Tendonitis 

Lithotripter outcomes in a community practice setting: Comparison of an electromagnetic and an electrohydraulic lithotripter

Top Surgeon: SoftWave ‘a superior way to make tissue want to heal’

The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

,

Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

Treatment for osteonecrosis of the femoral head

Spark Wave® Therapy Improves Full Thickness Skin Defects

Extracorporeal shockwave: mechanisms of action and physiological aspects…

Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

Is Shockwave Therapy Covered by Insurance? A Reimbursement Guide for Providers

Equine extracorporeal shock wave therapy

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

,

MTS Science White Paper – Softwave – Pain Therapy

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Acoustic Wave Therapy and Multiple Symmetric Lipomatosis

Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway

Linear Shockwave Therapy in Clinical Practice- Evidence and Mechanisms

Linear Shockwave Therapy Mechanisms and Efficacy Explained

Shock wave therapy causes increased macrophage recruitment and enhances M2 polarization

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Zapping chronic tendon pain

Extracorporal SoftWave Treatment to Improve Nerve Regeneration

,
Shockwave Therapy for Muscle Pain and Injuries

Shockwave Therapy for Muscle Pain and Injuries

Focused vs Radial Shockwave Therapy Machines Explained 

The Role of Shockwaves in the Enhancement of Bone Repair – From Basic Principles to Clinical Application

Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure

Letter regarding non unions in Europe. Dr. Schaden managing Director of the Workman’s Compensation Insurance Organization in Austria

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

, ,

Dr Irwin Goldstein Dinner Presentation – Nashville

Acoustic wave therapy for cellulite, body shaping and fat reduction.

Effects of ESWT on glycosaminoglycan expression during bone healing

What Is Pulse Wave Therapy & Does It Work for Patients?

What Is Pulse Wave Therapy & Does It Work for Patients?

Extracorporeal shockwave therapy for treatment of keloid scars

Shock wave treatment induces angiogenesis and mobilizes endogenous cd31/cd34-positive endothelial cells in a hindlimb ischemia model: implications for angiogenesis and vasculogenesis

,
Integrating Regenerative Treatments for Ankle Pain in Active Patients

Integrating Regenerative Treatments for Ankle Pain in Active Patients

Extracorporeal shock wave therapy (ESWT) for wound healing: Technology, mechanisms, and clinical efficacy

Golfer’s Secret Weapon for Injury Prevention: SoftWave TRT

,
Expanding Non-Surgical Treatment Options for Meniscus Injuries in Clinical Practice

Expanding Non-Surgical Treatment Options for Meniscus Injuries in Clinical Practice

Become a ProviderFind a Provider

Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

Click here to read more.
Read More

LL37 and shock waves

Click here to read more.
Read More

IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

Click here to read more.
Read More

Biological Principles – Mechanotransduction

Click here to read more.
Read More

Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
Read More

​The biologic effects of SoftWaves and rationale for spine and brain therapy

Click here to read more.
Read More

IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
Read More

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
Read More

Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
Read More

Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
Read More

Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
Read More

Latest Basic Research Abstracts

Click here to read more.
Read More

Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
Read More

Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
Read More

Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
Read More

Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
Read More

Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
Read More

Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
Read More

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
Read More
Become a ProviderFind a Provider